A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
Blog Article
Rotary movement of DNA rotors on nanopores. Prime row: raw movie from the Cy5 channel of each rotor. Center row: corresponding single-particle localization benefits of each finishes in the DNA rotors. The posture of the current body is marked as orange and blue dots, as well as the trajectory of The ten frames just before The existing frame is demonstrated as strong strains.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
2007, initial serious-time detection of strand exchange in homologous recombination by RecA; discovery of a small persistence length of ends of microtubules; and solved the system of biosensing with carbon nanotubes
We establish place-of-care diagnostics check of neglected tropical diseases in just useful resource-minimal options, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.
The coiled-coil of your human Rad50 DNA repair service protein includes specific segments of greater versatility
We form germs into forms that deviate from their natural phenotype. Precisely, I'll demonstrate our capability to shape live E. coli microbes into novel styles for example rectangles, squares, triangles and circles.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, as well as a 3D rendering of your motion of your DNA rod is displayed.
2003, demonstrated the first biosensors made outside of a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a https://www.ceesdekker.net brand new method for fabricating solid-point out nanopores for DNA translocation
‘The fantastically delicate way by which elements in mother nature purpose never ever ceases to amaze me. If we fix the puzzle of how existence came into remaining, I be expecting that my amazement with the complexity of creation should have greater and with it my awe to the greatness from the Creator.’
Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim of the pore is highlighted in pink, and also a 3D rendering with the motion from the DNA rod is displayed.
2006, initial demonstration of molecular sorting in the lab with a chip using biomotors; discovery of nanobubbles in reliable-point out nanopores; and first estimate of electrokinetic Vitality conversion in the nanofluidic channel
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of lengthy-array conformational modifications in Mre11/DNA repair service complexes; and initial pressure measurements on a DNA molecule within a nanopore
It was an incredibly interesting time, in the course of which I gained a lot of help from Delft College of Technological know-how, in which I used to be a professor at some time, And that i began many collaborations with molecular biologists. That aided me learn a great deal.’